Using light to investigate chemistry and biology

 

Interests:

Chemical biology, Photocatalysis, Protein engineering

 

News

December 2022: Our manuscript on using deep-red photoredox catalysis for overcoming photocatalytic limitations in metallaphotoredox C–N cross-coupling is now in JACS. Congrats to first author Sam G. and the entire team at BMS!

October 2022: Our preprint on using deep-red photoredox catalysis for live-cell protein environment labeling is now in Nature Chemistry. Congrats to co-first author Nari R., computational collaborator Jack, and the rest of the team at Merck Exploratory Science Center and Columbia University!

January 2022: Our manuscript detailing the rational development and tuning of osmium (II) photocatalysts is published in Synlett. Congrats to first author Sam G. and the rest of the team at Columbia and BMS!.

December 2021: Our method for site-selective arene halide exchange with fluoride (19F–) and radioactive fluoride (18F–) is published in Nature Chemistry. Congrats to first author Wei C. and the rest of our collaborators in the Nicewicz and Li labs.

November 2021: Our review on the critical comparisons between photoredox catalysis and electrochemistry for organic synthesis is live on Chemical Reviews. Congrats to Dan L. for the collaboration!

October 2021: Preprint on the rational development of osmium (II) photocatalysts to tune their excited- and ground- state redox properties is live on ChemRxiv. Congrats to first author Sam G. and the rest of the team at Columbia and BMS!.

October 2021: Preprint on using deep-red photoredox catalysis for live-cell protein environment labeling is live on ChemRxiv. Congrats to co-first author Nari R., computational collaborator Jack, and the rest of the team at Merck Exploratory Science Center

April 2021: Glad to share our contributions towards assay for testing COVID-19 protease inhibitors is published in the Journal of Virology. Congrats to first author Sam, R. the Stockwell, Ho and Chavez labs!

October 2020: Our report on using deep red and near infrared photoredox catalysis with osmium(II) photocatalysts with deep red or near infrared light is published in ACS Central Science. Congrats to Ben R. and our collaborators at BMS.

August 2020: The site-selective arene deoxyfluorination with fluoride (19F–) and radioactive fluoride (18F–) enabled by organic photoredox catalysis is published in Nature Catalysis. Congrats to co-first authors Wei C. and Alison L., as well as Vince P. and the rest of our collaborators from the Li lab at BRIC.

March 2020: Preprint on photoredox catalysis using the spin-forbidden excitation of osmium (II) photocatalysts with deep red or near infrared light is live on ChemRxiv. Congrats to Ben R. and our collaborators at BMS.