Preprints

Reports/Articles/Reviews

13. Goldschmid, S. L.; Tay, N. E. S.; Joe, C. L.; Lainhart, B. C.; Sherwood, T. C.; Simmons, E. M.; Sezen-Edmonds, M.; Rovis, T.

Overcoming Photochemical Limitations in Metallaphotoredox Catalysis: Red-Light-Driven C–N Cross-Coupling J. Am. Chem. Soc. 2022 144, 22409–22415.

12. Tay, N. E. S.*; Ryu, K. A.*; Weber, J.; Olow, A.; Cabanero, D. C; Reichman, D.; Oslund, R.; Fadeyi, O.; Rovis, T.

Targeted Activation in Localized Protein Environments via Deep Red Photoredox Catalysis. Nature Chemistry 2023, 15, 101–109. *denotes equal contribution.

11. Liu, H.; Iketani, S.; Khanizeman, N.; Bednarova, E.; Forouhar, F.; Fowler, B.; Hong, S. J.; Mohri, H.; Nair, M. S.; Huang, Y. Tay, N. E. S….Rovis, T.; Chavez, A. Ho, D. D.; Stockwell, B. R.

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nat. Commun. 2022 13, 1891.

10. Goldschmid, S.; Bednarova, E.; Beck, L.; Xie, K.; Tay, N.; Ravetz, B.; Li, J.; Joe, C.; Rovis, T.

Tuning the Electrochemical and Photophysical Properties of Osmium-Based Photoredox Catalysts. Synlett 2022 33, 247-258.

9. Chen, W.; Wang, H.; Tay, N. E. S.; Pistritto, V. A.; Li, K.-P.; Zhang, T.; Wu, Z.; Nicewicz, D. A.; Li, Z. Arene Radiofluorination Enabled by Photoredox-Mediated Halide Interconversion. Nature Chemistry 2022 14, 216–223.

8. Tay, N. E. S.; Lehnherr, D.; Rovis, T.

Photons or Electrons? A Critical Comparison of Electrochemistry and Photoredox Catalysis for Organic Synthesis. Chemical Reviews 2022, 122, 2, 2487–2649

7. Resnick, S. J.; Iketani, S.; Hong, S. J.; Zask, A.; Liu, H.; Kim, S.; Melore, S.; Lin, F-Y.; Nair, M. S.; Huang, Y.; Lee, S.; Tay, N. E. S.; Rovis, T.; Yang, H. W.; Stockwell, B. R.; Ho, D. D.; Chavez, A. A

Simplified Cell-Based Assay to Identify Coronavirus 3CL Protease Inhibitors. Journal of Virology 2021, 95, e02374-20.

6. Ravetz, B. D.; Tay, N. E. S.; Joe, C. L.; Schmidt, M. A.; Tan, Y.; Janey, J. M.; Eastgate, M.; Rovis, T.

Development of a Platform for Near-Infrared Photoredox Catalysis. ACS Central Science 2020, 6, 2053–2059.

5. Tay, N. E. S.*; Chen, W.*; Levens, A.*; Pistritto, V. A.; Huang, Z.; Wu, Z.; Li, Z.; Nicewicz, D. A.

19F- and 18F-Arene Deoxyfluorination via Organic Photoredox-Catalysed Polarity-Reversed Nucleophilic Aromatic Substitution. Nature Catalysis 2020, 3, 734–742.

*denotes equal contribution.

4. Tay, N. E. S.*; Chen, W.*; Huang, Z.*; Giglio, B.; Wang, M.; Wu, Z.; Nicewicz, D. A.; Li, Z.

Arene C-H Fluorination with 18F- via Organic Photoredox Catalysis Science, 2019, 364, 1170. *denotes equal contribution

3. Tay, N. E. S.; Nicewicz, D. A.

Cation Radical-Accelerated Nucleophilic Aromatic Substitution via Organic Photoredox Catalysis. J. Am. Chem. Soc., 2017, 139, 16100.

2. Romero, N. A.; Margrey, K. A.; Tay, N. E. S.; Nicewicz, D. A.

Site-selective Arene C-H Amination via Photoredox Catalysis. Science, 2015, 349, 6254.

1. Ernst, J. B.; Tay, N. E. S.; Jui, N. T.; Buchwald, S. L.

Regioselective Synthesis of Benzimidazolones via Cascade C−N Coupling of Monosubstituted Ureas. Org. Lett., 2014, 16, 3844–3846.

Patents

1. Nicewicz, D. A.; Romero, N. A.; Margrey, K. A.; Tay, N. E. S. “Photoredox-catalyzed direct c-h functionalization of arenes” US Patent #US20180148414A1